pentobarbital will reduce the level or effect of trazodone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will lower the level or impact of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Remark: Barbiturates may well increase adverse effects, including respiratory depression, made by harmful doses of TCAs. With therapeutic doses of TCAs, barbiturates boost metabolism and reduce blood concentrations of TCAs.
fentanyl intranasal and pentobarbital both equally enhance sedation. Keep away from or Use Alternate Drug. Limit use to clients for whom substitute therapy options are insufficient
pentobarbital will reduce the level or result of etravirine by affecting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Monitor.
Remark: Barbiturates may perhaps maximize adverse effects, like respiratory depression, made by harmful doses of TCAs. With therapeutic doses of TCAs, barbiturates boost metabolism and reduce blood concentrations of TCAs.
pentobarbital will reduce the level or effect of flurbiprofen by influencing hepatic enzyme CYP2C9/ten metabolism. Minimal/Importance Not known.
pentobarbital will raise the degree or impact of clopidogrel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will decrease the level or impact of stiripentol by affecting hepatic/intestinal here enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. If unable to prevent coadministration of stiripentol with potent CYP3A4 inducers, raise stiripentol dose.
Therapy really should be administered with warning, if in any way, to people that are mentally depressed, have suicidal tendencies, or background of drug abuse
Observe Intently (1)pentobarbital will minimize the level or effect of mestranol by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the extent or outcome of buspirone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will minimize the extent or influence of dienogest/estradiol valerate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Females should not pick out estradiol valerate/dienogest as their contraceptive when working with sturdy CYP3A4 inducers on account of prospective decrease in contraceptive efficacy.
pentobarbital will reduce the extent or influence of paclitaxel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.